. Author manuscript; available in PMC: 2014 Apr 24.

Published in final edited form as: J Immunol. 2008 Apr 15;180(8):5662–5669. doi: 10.4049/jimmunol.180.8.5662

Table I.

Enzyme Inhibitors

Enzyme Inhibited	Chemical Composition (manufacturer)	Specificity	Ref.
PE	Z-prolyl prolinal (Calbiochem)	K_I =500 pM	14
MMP-8	(3R)-(+)-[2– 4-methoxybenzenesulfonyl)-1,2,3,4-tetrahydroisoquinoline-3-hydroxamate] (Calbiochem)	IC₅₀ =4 nM	15
MMP-9	C₂₇H₃₃N₃O₅S (Calbiochem)	IC₅₀ =5 nM	16
MMP-2	cis-9-octadecenoyl-N-hydroxylamide (Calbiochem)	Ki = 1.7 μM	17
HNE	N-(2-(4-(2,2-dimethylpropionyloxy) phenylsulfonylamino)benzoyl) aminoacetic acid N-(o-( p-pivaloyloxybenzene) sulfonylaminobenzoyl) glycine (Calbiochem)	IC₅₀ =50 nM	18
Nonspecific MMP	Doxycycline (Calbiochem)	Nonspecific MMP inhibitor	19