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. 2014 Mar 31;16(8):2122–2125. doi: 10.1021/ol5005438

Scheme 3. Proposed Mechanistic Model.

Scheme 3

Formation of compounds 6 and 8 might be two branching pathways in OvoA catalysis. It may involve either a sulfenic acid intermediate (11, Path A) or thiother intermediate (12, Path B). Formations of 6 and 8 may branch out from either the peroxy radical species (10, Path C) or the sulfenic acid intermediate (11, Path D).