Table 5.
Relation of the Apo B Gene Genotype with the Lipid and Polipoprotein Spectrum of Blood in the Uighurs with Coronary Heart Disease (CHD)
| Parameters (mmol/l) | X1X1 (n-48) | X1X2 (n-25) | X2X2 (n-7) | P1 | P2 | P3 |
|---|---|---|---|---|---|---|
| TC (mmol/l) | 5.50 ± 0.12 | 5.60 ± 0.15 | 6.2 ± 0.21 | >0,05 | <0,05 | <0,05 |
| HDLC | 1.18 ± 0.04 | 1.19 ± 0.06 | 1.16 ± 0.11 | >0,05 | >0,05 | >0,05 |
| LDLC | 3.91± 0.10 | 4.0 ± 0.13 | 4.64 ± 0.20 | >0,05 | <0,05 | <0,05 |
| VLDLPC | 0.41 ± 0.02 | 0.41 ± 0.04 | 0.4 ± 0.05 | >0,05 | >0,05 | >0,05 |
| TG | 2.04 ± 0.08 | 2.04 ± 0.09 | 1.98 ± 0.14 | >0,05 | >0,05 | >0,05 |
| AI | 3.66 ± 0.14 | 3.71 ± 0.15 | 4.34 ± 0.23 | >0,05 | <0,05 | <0,05 |
| Apo A1 (mg/dl) | 130.6 ± 2.2 | 128.1 ± 3.7 | 127.2 ± 4.1 | >0,05 | >0,05 | >0,05 |
| Apo B (mg/dl) | 88.98 ± 2.63 | 93.09 ± 2.97 | 107.4 ± 3.45 | >0,05 | <0,05 | <0,05 |
| Apo E (mg/dl) | 4.3 ± 0.10 | 3.9 ± 0.16 | 3.7 ± 0.28 | >0,05 | >0,05 | >0,05 |
Note: P1 – Statistical differences of lipid parameters in patients with the X1X1 and X1X2 genotypes, P2 - Statistical differences of lipid parameters in patients with the X1X1 and X2X2 genotypes, P3 - Statistical differences of lipid parameters in patients with the X1X2 and X2X2 genotypes.