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The cytotoxic effects of free SHK, free PLGA NPs, SHK-loaded PLGA NPs, and SHK-loaded PEGylated PLGA NPs in primary T-cells.
Notes: T-cells were exposed to SHK for 2 hours and then sulforhodamine B cytoto xicity assay was conducted. *Statistical significance (P<0.05).
Abbreviations: NPs, nanoparticles; PLGA, poly(lactic-co-glycolic acid); SHK, shikonin; PEG, polyethylene glycol.
