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. 2014 Apr 24;8(4):e2795. doi: 10.1371/journal.pntd.0002795

Table 1. Baseline demographics of melioidosis patients on diabetic therapy.

Sulphonylurea (N = 44) Without Sulphonylurea (N = 30) P value
Gender
Male 39 (88.6%) 24 (80.0%) 0.336
Female 5 (11.4%) 6 (20.0%)
Median age 58.2 56.5 0.536
Immunocompromised state 2 (4.5%) 4 (13.3%) 0.215
Statin use 22 (50.0%) 10 (33.3%) 0.155
HbA1c# 9.00±2.30 9.59±2.64 0.353
Serum creatinine (µmol/L) 182±200 201±281 0.750
Bp culture positive* 34 (77.3%) 26 (86.7%) 0.377
Concurrent diabetic medication
Metformin 23 (52.3%) 14 (46.7%) 0.848
Insulin 3 (6.8%) 18 (60.0%) 0.001
Thiazolidinedione 1 (2.3%) 2 (6.7%) 0.562
α-glucosidase inhibitor 9 (20.5%) 0 (0%) 0.010
Complications
Hypotension (inotropes) 13 (29.5%) 1 (3.3%) 0.005
Intubation 9 (20.5%) 2 (6.7%) 0.182
Renal Failure 8 (18.2%) 2 (6.7%) 0.187
Septicaemia 9 (20.5%) 3 (10.0%) 0.339
Any (above) complications 21 (47.7%) 5 (16.7%) 0.006
Length of stay (days) 27.7 21.5 0.168
Mortality 7 (15.9%) 1 (3.3%) 0.080

#10 (of 44) patients from the sulphonylurea group and 3 (of 30) patients from the no-sulphonylurea group had no recent HbA1c measurements available.

* Burkholderia pseudomallei culture positive. Other cases were diagnosed by positive melioidosis serology >1/64 titres.