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. 2014 Apr 24;9(4):e95529. doi: 10.1371/journal.pone.0095529

Table 1. Values for photocytotoxic concentration (IC50, µM) of photoactivated PcGal16 on human bladder cancer cell lines, HT-1376 and UM-UC-3.

HT-1376 cell line UM-UC-3 cell line
Hours after PDT 24 48 72 24 48 72
IC50 (µM), CI95% - 3.3 [0.6;10.7] 2.5 [2.2;2.9] 2.1 [0.9;5.0] 2.8 [2.4; 3.2] 2.6 [2.6;2.7]

IC50 is the incubation concentration that inhibits the proliferation of cultures in 50%, after cells' incubation with PcGal16 and irradiation. IC50 values were calculated using the MTT dose response curves (24, 48, and 72 h after PDT), obtained for cells incubated with PcGal16 at various concentrations for 2 h.

CI95%: 95% Confidence interval.