Table 1. Values for photocytotoxic concentration (IC50, µM) of photoactivated PcGal16 on human bladder cancer cell lines, HT-1376 and UM-UC-3.
HT-1376 cell line | UM-UC-3 cell line | |||||
Hours after PDT | 24 | 48 | 72 | 24 | 48 | 72 |
IC50 (µM), CI95% | - | 3.3 [0.6;10.7] | 2.5 [2.2;2.9] | 2.1 [0.9;5.0] | 2.8 [2.4; 3.2] | 2.6 [2.6;2.7] |
IC50 is the incubation concentration that inhibits the proliferation of cultures in 50%, after cells' incubation with PcGal16 and irradiation. IC50 values were calculated using the MTT dose response curves (24, 48, and 72 h after PDT), obtained for cells incubated with PcGal16 at various concentrations for 2 h.
CI95%: 95% Confidence interval.