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. 2014 Apr 24;9(4):e96043. doi: 10.1371/journal.pone.0096043

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© 2014 Das et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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A. Total body weight. Total body weight of mice is significantly decreased by a 12 week-CCl₄ treatment. *p<0.001, CCl₄-treated vs. control animals. B. Spleen weight/body weight ratio. Increased ratio of spleen weight/total body weight in CCl₄-treated mice is consistent with spleen enlargement. Data are mean ± SEM. *p<0.002, CCl₄-treated vs. control mice. (n = 3 for control group; n = 7 for CCl₄-treated group).