Figure 4. CCl4-treament induces reductions in pulmonary artery acceleration time (PAT) and the ratio of PAT/PET.
A. Ultrasonographic images. Representative images of PA Doppler flow for control (left) and CCl4-treated (right) mice. Although the magnitude of the PET is identical, the PAT is markedly reduced in CCl4-treated mice. B. Quantification of PA hemodynamic parameters. Echocardiographic analysis was performed on control (n = 3) and CCl4-treated (n = 7) mice. Data are mean ± SEM per group. * p<0.01 CCl4-treated group vs control group.