Table III.
Multivariate analysis.
| Variables | Bladder cancer-specific mortality | Distant metastasis | ||||
|---|---|---|---|---|---|---|
|
|
|
|||||
| HR | P-value | 95% CI | HR | P-value | 95% CI | |
| Tumor stage | ||||||
| II | Reference | Reference | ||||
| III-IV | 1.5 | 0.63 | 0.31–7.0 | 1.1 | 0.90 | 0.18–6.9 |
| Vascular invasion | ||||||
| No | Reference | Reference | ||||
| Yes | 1.2 | 0.89 | 0.27–4.8 | 2.3 | 0.29 | 0.50–10.2 |
| Hydronephrosis | ||||||
| No | Reference | Reference | ||||
| Yes | 1.9 | 0.40 | 0.43–8.4 | 3.7 | 0.12 | 0.72–18.7 |
| RRM1 expression | ||||||
| Low | Reference | Reference | ||||
| High | 3.0 | 0.15 | 0.69–12.8 | 1.7 | 0.52 | 0.35–7.8 |
HR, hazard ratio; CI, confidence interval; RRM1, ribonucleoside reductase subunit M1.