Table IV.
P-values and the correlation coefficients between the drinking years and the mRNA expression of 5-FU-related metabolic enzymes.
| Enzymes | P-value | Correlation coefficient |
|---|---|---|
| TS | ||
| Tumor | 0.6687 | 0.084 |
| Normal | 0.3528 | 0.818 |
| DPD | ||
| Tumor | 0.0444 | 0.375 |
| Normal | 0.0202 | 0.426 |
| OPRT | ||
| Tumor | 0.2879 | 0.205 |
| Normal | 0.3902 | 0.167 |
| TP | ||
| Tumor | 0.1286 | 0.290 |
| Normal | 0.9183 | 0.020 |
5-FU, 5-fluorouracil; TS, thymidylate synthase; DPD, dihydropyrimidine dehydrogenase; OPRT, orotate phosphoribosyl transferase; TP, thymidine phosphorylase.