Table II.
Tumor response and disease control.
| Patient no. | Chemotherapy cycles | Intracranial tumor response | Neurological symptoms | Extracranial tumor response | Intracranial disease control (survival, days) | Extracranial disease control (survival, days) | Interval between therapy and death or last follow-up (days) |
|---|---|---|---|---|---|---|---|
| 1 | 6 | PR | - | PR | 179 | 179 | 179 |
| 2 | 5 | PR | - | PR | 206 | 114 | 236 |
| 3 | 3 | PR | Improved | PD | 92 | 51 | 109 |
| 4 | 3 | SD | - | PD | 107 | 59 | 107 |
| 5 | 4 | PR | - | PR | 287 | 287 | 287 |
| 6 | 1 | PR | Improved | SD | 144 | 201 | 232 |
| 7 | 5 | PR | - | NA | 212 | - | 212 |
| 8 | 1 | PD | - | PD | 23 | 23 | 141 |
| 9 | 6 | PR | Improved | SD | 189 | 274 | 274 |
PR, partial response; PD, progressive disease; SD, stable disease; NA, not-applicable. Patient no. 6 achieved a complete remission of the cranial tumor after cranial radiotherapy.