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. Author manuscript; available in PMC: 2015 Apr 1.
Published in final edited form as: Cytokine Growth Factor Rev. 2014 Jan 10;25(2):107–113. doi: 10.1016/j.cytogfr.2014.01.001

Figure 1.

Figure 1

Systemic BLyS levels afford survival of only B cells with sub-threshold BCR signals at the transitional checkpoint (left), while TFH-produced BLyS selectively spares antigen-presenting GC B cells with very strong BCR signals (right).