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. Author manuscript; available in PMC: 2015 Apr 15.
Published in final edited form as: J Acquir Immune Defic Syndr. 2014 Apr 15;65(5):e179–e186. doi: 10.1097/QAI.0000000000000075

Table 2.

Selected key model parameters.

Distribution and value Source
HIV-related mortality Double Weibull B2C
    Shape 1 1.340
    Scale 1 0.199
    Shape 2 0.719
    Scale 2 40.557
    Weight of 1st component 0.031
Official transfer out Weibull B2C
    Shape 1.015
    Scale 8.196
Self-transfer out Weibull B2C
    Shape 1.637
    Scale 32.813
Changing to alternative ART sources Weibull B2C
    Shape 1.207
    Scale 21.785
ART discontinuation Weibull B2C
    Shape 0.666
    Scale 43.102
Probabilities of missing an event B2C
    Death 0.583
    Official transfer out 0.140
    ART discontinuation 0.900
Spontaneous return Exponential assumption
    Rate 0.333
Probability to be found by tracing B2C
    If discontinued ART or on irregular ART 0.700
Return after tracing if discontinued ART Weibull B2C
    Shape 0.476
    Scale 2.74
Return after tracing if on irregular ART Weibull B2C
    Shape 0.574
    Scale 0.599
Partner change assumption
    Rate 1
Frequency of sex acts assumption
    Acts per year 100
Per-act probability of transmission From Wilson et al.5
    Male to female, viral load 10 copies/ml 4.3*10−5
    Female to male, viral load 10 copies/ml 2.2*10−5
    Risk ratio per 1 log10 increase in viral load 2.45

ART, antiretroviral therapy; LH, Lighthouse Clinic (longitudinal data from leDEA Southern Africa database); B2C, Back-to-Care tracing programme7. Weibull distribution is parameterised using the following formula for cumulative incidence (CI): Cl(t)=1e(tλ)k, where k is the shape parameter and λ the scale parameter. Double Weibull distribution is a mixture of two Weibull distributions.