Table 2.
Selected key model parameters.
| Distribution and value | Source | |
|---|---|---|
| HIV-related mortality | Double Weibull | B2C |
| Shape 1 | 1.340 | |
| Scale 1 | 0.199 | |
| Shape 2 | 0.719 | |
| Scale 2 | 40.557 | |
| Weight of 1st component | 0.031 | |
| Official transfer out | Weibull | B2C |
| Shape | 1.015 | |
| Scale | 8.196 | |
| Self-transfer out | Weibull | B2C |
| Shape | 1.637 | |
| Scale | 32.813 | |
| Changing to alternative ART sources | Weibull | B2C |
| Shape | 1.207 | |
| Scale | 21.785 | |
| ART discontinuation | Weibull | B2C |
| Shape | 0.666 | |
| Scale | 43.102 | |
| Probabilities of missing an event | B2C | |
| Death | 0.583 | |
| Official transfer out | 0.140 | |
| ART discontinuation | 0.900 | |
| Spontaneous return | Exponential | assumption |
| Rate | 0.333 | |
| Probability to be found by tracing | B2C | |
| If discontinued ART or on irregular ART | 0.700 | |
| Return after tracing if discontinued ART | Weibull | B2C |
| Shape | 0.476 | |
| Scale | 2.74 | |
| Return after tracing if on irregular ART | Weibull | B2C |
| Shape | 0.574 | |
| Scale | 0.599 | |
| Partner change | assumption | |
| Rate | 1 | |
| Frequency of sex acts | assumption | |
| Acts per year | 100 | |
| Per-act probability of transmission | From Wilson et al.5 | |
| Male to female, viral load 10 copies/ml | 4.3*10−5 | |
| Female to male, viral load 10 copies/ml | 2.2*10−5 | |
| Risk ratio per 1 log10 increase in viral load | 2.45 |
ART, antiretroviral therapy; LH, Lighthouse Clinic (longitudinal data from leDEA Southern Africa database); B2C, Back-to-Care tracing programme7. Weibull distribution is parameterised using the following formula for cumulative incidence (CI): , where k is the shape parameter and λ the scale parameter. Double Weibull distribution is a mixture of two Weibull distributions.