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. Author manuscript; available in PMC: 2014 Oct 1.
Published in final edited form as: Genes Immun. 2014 Jan 23;15(3):145–152. doi: 10.1038/gene.2013.74

Figure 4.

Figure 4

Parasitemia and mortality of wild type (wt) and cytokine/chemokine gene knockout (−/−) mice infected with Plasmodium yoelii nigeriensis N67. Mice (n = 5–8) were injected intravenously with an inoculum containing 1×105 infected red blood cells. Parasitemias were measured daily by microscopic examination of Giemsa-stained thin tail blood smears. (a–e) Red lines, wt mice; black lines, −/− mice. (a) MIG−/−; (b) IP-10−/−; (c) CXCR3a−/−; (d) IL-10−/−; (e) MCP-1−/−. (f) Mice showing severe clinical signs were humanely euthanized; the numbers of surviving mice during the course of infection were used to calculate percentage of survival.