Skip to main content
. Author manuscript; available in PMC: 2015 May 1.
Published in final edited form as: Alcohol Clin Exp Res. 2014 Mar 3;38(5):1390–1400. doi: 10.1111/acer.12378

Figure 5.

Figure 5

Effects of maternal ethanol exposure on cirmiRNA profiles in 3rd-trimester-equivalent pregnant ewe and newborn lamb. (a) CirmiRNAs that passed FDR-corrected ANOVAs (α=0.05) were subjected to Euclidean Cluster analysis with average linkage and rows centering on miRNAs, showing that the in utero ethanol-exposed newborn lamb was different from all other groups. (b) PCA(component-1) separated the in utero ethanol exposed lamb from all other groups, whereas PCA(component-2) separated the ethanol-exposed pregnant ewe from both control groups (pregnant ewe and newborn lamb). Sample size = 4 each for ethanol-treated and control pregnant ewes and = 6 each for control and in utero ethanol-treated lamb.