Table 1.
Demographics, MRI characteristics of healthy males and females.
| Entire Healthy Group (N=105) | Males (M=49) | Females (F=56) | p (M vs. F) | |
|---|---|---|---|---|
|
| ||||
| Age in years: | ||||
| Mean ± S. D. | 34.8 ± 10.6 | 33.1 ± 10.5 | 36.3 ± 10.5 | 0.12 |
| [Range] | [18.7 – 57.6] | [18.7 – 57.6] | [19 – 56.9] | |
| Median | 33.7 | 30.7 | 35.8 | |
|
| ||||
|
Intracranial Volume (mL) Mean ± S. D. |
1529.4 ± 136.2 | 1620.6 ± 109.7 | 1449.6 ± 103.4 | 1×10−12 |
|
| ||||
| Sulcal CSF Volume(mL) | 119.8 ± 42.7 | 131.7 ± 45.9 | 109.4 ± 37 | 0.007 |
|
| ||||
| sCSFp (sCSFv/ICV*100%) | 7.81 ± 2.57 | 8.11 ± 2.68 | 7.54 ± 2.47 | 0.26 |
|
| ||||
| LVV (mL) | ||||
| SPM-DTI | 11.42 ± 4.44 | 12.21 ± 4.72 | 10.73 ± 4.11 | 0.09 |
| FreeSurfer | 11.40 ± 4.66 | 12.05 ± 4.80 | 10.84 ± 4.50 | 0.19 |
|
| ||||
| LVVp | ||||
| SPM-DTI | 0.749 ± 0.292 | 0.759 ± 0.306 | 0.741 ± 0.282 | 0.76 |
| FreeSurfer | 0.748 ± 0.307 | 0.749 ± 0.312 | 0.748 ± 0.306 | 0.99 |
|
| ||||
| MD(LV) | 2.844 ± 0.00071 | 2.862 ± 0.00062 | 2.828 ± 0.00075 | 0.02 |
|
| ||||
| FA(LV) | 0.091 ± 0.012 | 0.089 ± 0.011 | 0.092 ± 0.012 | 0.22 |
Abbreviations
ICV = Intracranial volume (mL)
LVV= lateral ventricular volume (mL)
LVVp = Lateral ventricular volume to total intracranial volume percentage = LVV/ICV (×100%)
S.D. = standard deviation; M = males, F = females
FA = Fractional anisotropy
MD = Mean diffusivity (mm2 sec−1).
sCSF = sulcal or non-ventricular CSF