Table 1.
LPV/r (n=91*) | NNRTI (n=92*) | P-value† | |
---|---|---|---|
Age, years | 3.1 (2.4 to 4.3) | 3.1 (2.4 to 4.7) | 0.63 |
Female | 44 (48%) | 45 (48%) | 0.53 |
WHO Stage | 0.82 | ||
I | 64 (70%) | 70 (76%) | |
II | 19 (21%) | 16 (17%) | |
III | 2 (2%) | 1 (1%) | |
IV | 6 (7%) | 5 (5%) | |
ART-status | 0.55 | ||
ART-naïve | 64 (70%) | 65 (71%) | |
ART-experienced | 27 (29%) | 27 (29%) | |
CD4 number, cells/μl | |||
ART-naïve | 582 (597 to 969) | 593 (389 to 788) | 0.89 |
ART-experienced | 1275 (861 to 1885) | 1099 (802 to 1906) | 0.59 |
CD4 Percentage | |||
ART-naïve | 17 (12 to 23) | 16 (11 to 23) | 0.77 |
ART-experienced | 31 (27 to 38) | 30 (24 to 37) | 0.60 |
HIV RNA Level, log(copies/ml) | |||
ART-naïve | 5.3 (4.8 to 5.9) | 5.5 (4.8 to 5.9) | 0.75 |
ART-experienced | All BLD | All BLD | - |
Excludes the 2 children who withdrew or died before initiating study drugs.
Student's T-Test or Chi-square.
Values are medians (interquartile range) or number (percentage); LPV/r, ritonavir-boosted lopinavir; NNRTI, non-nucleoside-reverse-transcriptase-inhibitor; BLD, below level of detection, 400 copies/ml.