Table 3.
Parameter | Pre-term birth | Birth weight (g) | Peripartum events scale | Peripartum events scale ≥ 1 | Peripartum events scale ≥ 2 | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
OR | 95% CI | p-value | β | 95% CI | p-value | β | 95% CI | p-value | OR | 95% CI | p-value | OR | 95% CI | p-value | |
GCT, unadjusted | 0.986 | 0.826–1.176 | 0.8715 | 19.6 | -16.2 to 55.4 | 0.2839 | 0.084 | -0.004 to 0.172 | 0.0610 | 1.017 | 0.893–1.158 | 0.7993 | 1.150 | 0.932–1.419 | 0.1938 |
GCT, adjustedb | 1.290 | 1.001–1.661 | 0.0488 | -28.5 | -68.3 to 11.3 | 0.1608 | 0.107 | 0.004–0.210 | 0.0420 | 1.040 | 0.884–1.223 | 0.6355 | 1.250 | 0.931–1.680 | 0.1382 |
GCTa diagnosis, unadjusted | 0.2424 | 0.3566 | 0.1330 | 0.4735 | 0.4389 | ||||||||||
Healthy control | 0.785 | 0.452–1.361 | 0.3879 | 32.8 | -34.9 to 100 | 0.3429 | 0.089 | -0.099 to 0.278 | 0.3529 | 1.034 | 0.801–1.336 | 0.7965 | 1.196 | 0.741–1.929 | 0.4642 |
Bipolar disorder | 0.817 | 0.537–2.020 | 0.9048 | 33.6 | -91.3 to 93.1 | 0.9854 | -0.181 | -0.594 to 0.053 | 0.1006 | 0.805 | 0.509–1.189 | 0.2463 | 0.811 | 0.327–1.410 | 0.2987 |
Prior MDD | 1.295 | 0.854–3.192 | 0.1363 | -47.2 | -185 to 25.1 | 0.1359 | 0.140 | -0.195 to 0.296 | 0.6851 | 1.073 | 0.714–1.507 | 0.8487 | 1.280 | 0.580–1.979 | 0.8266 |
Current MDD | 1.018 | 0.684–2.460 | 0.4260 | 38.3 | -91.8 to 103 | 0.9118 | 0.135 | -0.210 to 0.300 | 0.7287 | 1.080 | 0.728–1.497 | 0.8157 | 1.344 | 0.568–2.227 | 0.7362 |
GCTa diagnosis, adjustedb | 0.3248 | 0.3530 | 0.2498 | 0.6144 | 0.3342 | ||||||||||
Healthy control | 1.021 | 0.577–1.805 | 0.9434 | -3.2 | -71.2 to 64.7 | 0.9259 | 0.121 | -0.086 to 0.327 | 0.2513 | 1.004 | 0.751–1.343 | 0.9787 | 1.529 | 0.893–2.617 | 0.1218 |
Bipolar disorder | 1.025 | 0.486–2.072 | 0.9922 | -16.7 | -108 to 80.8 | 0.7796 | -0.181 | -0.703 to 0.100 | 0.1406 | 0.839 | 0.506–1.379 | 0.4820 | 0.543 | 0.085–1.491 | 0.1574 |
Prior MDD | 1.714 | 0.829–3.401 | 0.1502 | -90.7 | -190 to 15.3 | 0.0953 | 0.177 | -0.204 to 0.316 | 0.6733 | 1.135 | 0.752–1.700 | 0.5555 | 1.351 | 0.442–1.765 | 0.7261 |
Current MDD | 1.261 | 0.622–2.453 | 0.5457 | -13.1 | -106 to 86.7 | 0.8415 | 0.088 | -0.313 to 0.247 | 0.8167 | 1.096 | 0.734–1.623 | 0.6656 | 1.048 | 0.293–1.604 | 0.3840 |
OR = odds ratio; CI = confidence interval; GCT = glucose challenge test; MDD = major depressive disorder.
GCT modeled in increments of 10.
Adjusted for age, education, employment, marital status, pre-pregnancy body mass index, tobacco, illicit drug use, psychiatric and, metabolism-changing medications.