Figure 1.

Neutrophil infiltration during infarct healing. (A and B) Neutrophils were identified in the left ventricular myocardium (LV) by their distinctive multi-lobed nuclei in haematoxylin and eosin-stained sections, counted and expressed as number per 10 μm². (B) Tiled heart 2 days post-infarction showing neutrophil invading infarct border. IA, infarct area; RV, right ventricle. Arrows point to neutrophils. n = 8, C57BL/6 sham; n = 12, C57BL/6 MI; n = 4, 11βHSD1^−/− sham; n = 6, 11βHSD1^−/− MI. ^##P < 0.01, ^###P < 0.001 (versus matched sham), **P < 0.01 (C57BL/6 versus 11βHSD1^−/−). Scale bar, 10 μm.