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Heart function during and after infarct healing. Ejection fraction was calculated from the LV end-diastolic area (LVEDA) and LV end-systolic area (LVESA) and expressed as a percentage. Data are presented as mean ± SEM, lighter columns C57BL/6, darker columns 11βHSD1−/−. (for C57BL/6, n = 12 MI during early healing at 2, 4, and 7 days after MI, n = 10 for MI at day 28; for 11βHSD1−/− n = 6 MI day 2, 4, and 7, and n = 9 for MI day 28). *P < 0.05, **P < 0.01 C57BL/6 versus 11βHSD1−/−.
