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. Author manuscript; available in PMC: 2014 Apr 25.
Published in final edited form as: Nat Commun. 2011 Jan 11;2:153. doi: 10.1038/ncomms1153

Figure 6. CatSperδ-null mice lack CatSper current.

Figure 6

(a) CatSperδ-het and (b) CatSperδ-null ICatSper. The upper traces show representative time courses of ICatSper measured in control solutions (1), nominally divalent-free (DVF) solutions (2), and high-K+ solutions (3) at −100 mV (open cicrles) and + 100 mV (closed circles). Bottom panels show the current-voltage relations of monovalent ICatSper in response to voltage ramps at the time points indicated. ICatSper is absent in CatSperδ-null sperm cells. A small inward IKSper was seen in both phenotypes when the bath solution was switched to 160 mM K-MeSO3. CatSperδ-het currents are indistinguishable from previously published wt currents1.