TABLE 3.

Brain Regions Involved in Empathy for Pain¹

Voxel	ALE	x	y	z	Area	Label
2405	0.084	−40	14	0		L anterior insula
	0.041	−30	−4	−14		L amygdala
	0.036	−16	−8	−8		L globus pallidus
	0.033	−38	−2	4		L claustrum
	0.029	−48	8	8	44	L precentral gyrus
	0.028	−46	0	24	9	L inferior frontal gyrus
	0.026	−38	−2	16		L posterior insula
2298	0.084	40	20	−4	47	R inferior frontal gyrus
	0.032	46	28	6	13	R inferior frontal gyrus
	0.032	26	−2	−14		R amygdala
1999	0.075	−2	24	32	32	L ACC/RCZa
	0.057	0	−2	36	24	ACC/CCZ
	0.050	−8	6	40	32	L ACC/RCZp
	0.031	0	10	54	6	L MPFC
506	0.053	52	−30	34	2	R SI
408	0.047	−54	−28	34	40	L inferior parietal lobule
	0.020	−44	−38	38	40	L inferior parietal lobule
302	0.033	12	−6	12		R thalamus
154	0.041	−2	42	18	9	L MPFC
150	0.028	−42	−68	−8	19	L fusiform gyrus
	0.027	−44	−72	6	19	L mid occipital gyrus
143	0.038	−38	−48	50	40	L inferior parietal lobule
131	0.040	36	−4	14		R posterior insula
117	0.027	48	4	30	9	R inferior frontal gyrus
	0.024	44	2	42	6	R mid frontal gyrus
55	0.026	−10	−12	6		L thalamus
40	0.028	30	−82	2	18	R mid occipital gyrus
35	0.027	−30	−64	−26		L cerebellum

¹P_FDR < 0.05, k > 30, voxel size = 2 × 2 × 2 mm. ACC, anterior cingulate cortex; RCZa, anterior rostral cingulate zone; RCZp, posterior rostral cingulate zone; CCZ, caudal cingulate zone; SI, primary somatosensory cortex; MPFC, medial prefrontal cortex; L, left; R, right. RCZa, RCZp, and CCZ are defined as by Fan et al. (2008).