Fig. 1.

The SCI principle. Changes in the optical thickness of a biolayer on a glass surface are recorded by a spectrum of interfering beams reflected from the sensor chip (A): 1 – air; 2 – microscopic glass cover slip; 3 – test solution; 4 – flow channel; 5 – receptor molecules; 6 – incident beam of superluminescent diode; 7,9 – reflected beams; 8 – position of the reflected beam before a biochemical reaction; 10 – detected biomolecules. (B): Photo of a three-channel Picoscope^® biosensor