Table 2. Relationship between antiretroviral therapy and treatment outcomes in HIV-infected TB patients.
| Time since starting TB treatment | Outcomes (%) | Treated with ART? | Patients treated with ART vs. patients not treated with ART | ||
|---|---|---|---|---|---|
| Yes | No | Relative risk (95% CI) | p-value | ||
| Total | 314 | 90 | |||
| One year |
Outcome known† Remaining under follow up‡ Died Transferred out Lost to follow up Stopped ART |
297 (95.2) 247 (83.2) 30 (10.1) 13 ( 4.4) 5 ( 1.7) 2 ( 0.7) |
86 (95.6) 41 (47.7) 29 (33.7) 13 (15.1) 3 ( 3.5) - |
0.57 ( 0.46 – 0.72) 3.34 ( 2.13 – 5.24) 3.45 ( 1.66 – 7.17) 2.07 ( 0.51 – 8.50) - |
<0.001 <0.001 0.001 0.386 |
| Two years |
Outcome known† Remaining under follow up‡ Died Transferred out Lost to follow up Stopped ART |
276 (87.9) 208 (75.4) 36 (13.0) 19 ( 6.9) 11 ( 4.0) 2 ( 0.7) |
79 (87.8) 22 (27.8) 30 (38.0) 18 (22.8) 9 (11.4) - |
0.37 ( 0.26 – 0.53) 2.91 ( 1.92 – 4.41) 3.31 ( 1.83 – 6.00) 2.86 ( 1.23 – 6.65) - |
<0.001 <0.001 <0.001 0.023 |
| Three years |
Outcome known† Remaining under follow up‡ Died Transferred out Lost to follow up Stopped ART |
241 (76.8) 159 (66.0) 40 (16.6) 24 ( 10.0) 13 ( 5.4) 5 ( 2.1) |
75 (83.3) 15 (20.0) 31 (41.3) 19 ( 25.3) 10 ( 13.3) - |
0.30 ( 0.19 – 0.48) 2.49 ( 1.69 – 3.68) 2.54 ( 1.48 – 4.38) 2.47 ( 1.13 – 5.41) - |
<0.001 <0.001 0.002 0.038 |
†
Outcome known = Number of patients at the given time period for whom the outcome is known according to duration of follow up. Follow up ranged from 6 months to five years, depending on time of entry to study.
‡
Remaining under follow up= Continuing to attend regular HIV clinics