. 2014 Apr 1;3(2):81–85. doi: 10.12860/jnp.2014.16

Table 1. Effect of different doses (mg/kg/day) of saffron on serum biochemical parameters in mice treated for three weeks .

Variable Parameter	Saline Control	5000	1000	2000
BUN (mg/dL)	37.43 ± 3.2	35.16 ± 2.51	58.5 ± 4.99*	70.31 ± 13.30**
Creatinine(mg/dL) (mg/dL)	0.41 ± 0.03	0.44 ± 0.04	0.37 ± 0.02	0.37 ± 0.1
ALT (IU/L)	67.36 ± 7.01	71.21 ± 6.41	58.16 ± 3.04	68.03 ± 8.06
AST (IU/L)	87.66 ± 9	99.33 ± 7.94	117.5 ± 14.24	123.4 ± 40.15
ALP (IU/L)	63.05 ± 8.23	62.61 ± 5.52	55.3 ± 4.94	58,65 ± 4.06
Total bilirubin(mg/dL) (mg/dL)	0.42 ± 0.01	0.39 ± 0.02	0.39 ± 0.03	0.38 ± 0.03

Data are shown as Mean± SEM (n =8). *p < 0.05, **p < 0.01, compared with control group. BUN: blood urea nitrogen, ALT: alanine aminotransferase, AST: aspartate aminotransferase, and ALP: alkaline phosphatase.