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. Author manuscript; available in PMC: 2014 Apr 25.
Published in final edited form as: J Immunol. 2010 May 17;184(12):7196–7206. doi: 10.4049/jimmunol.0901404

FIGURE 3.

FIGURE 3

Microhemodynamic parameters in the postcapillary venules of the inflamed spinal cord white matter in SJL mice with PLPaa 139–151-induced EAE. Hemodynamic parameters were determined in three to four mice per group in the indicated number of postcapillary venules. For immature DCs, IgG2b isotype control, n = 15 venules; PS/2, n = 9; Fib504, n = 7 venules; β1 integrin−/−, n = 19; and DATK32, n = 10 venules. For LPS-matured DCs, IgG2b isotype control, n = 9 venules and PS/2, n = 13 venules. A, Microvessel diameters in micrometers. B, Mean blood flow velocity (micrometers per second). C, Wall shear rate (s−1). D, Wall shear stress (dyne/cm). Each dot represents one analyzed postcapillary venule. Quantitative data are given as medians with interquartile ranges. Statistical significance was determined by the Mann-Whitney U test.