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. 2014 Apr;5(2):E46–E49. doi: 10.3978/j.issn.2078-6891.2014.012

Table 1. Cairo-Bishop definition of laboratory TLS for adults [adapted from reference (2)].

Variable Value Change from baseline value
Uric acid ≥8 mg/dL (476 micromol/L) 25% increase
Potassium ≥6.0 mEq/L (or 6 mmol/l) 25% increase
Phosphorus ≥4.5 mg/dL (1.45 mmol/L) for adults and ≥2.1 mmol/L (6.5 mg/dL) for children 25% increase
Calcium ≤7 mg/dL (1.75 mmol/L) 25% decrease

TLS, tumor lysis syndrome.