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. 2014 Mar 10;137(5):1524–1532. doi: 10.1093/brain/awu040

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© The Author (2014). Published by Oxford University Press on behalf of the Guarantors of Brain.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Scatterplots showing the relationships between vessel density, as measured by determining the area fraction immunopositive for FVIIIRA in histological sections of right parietal white matter, and both (A) FVIIIRA level and (B) VEGF concentration in the left parietal white matter. The vessel density correlated strongly with FVIIIRA concentration (r = 0.580, P < 0.0001) and tended to increase with VEGF concentration, although not significantly so. VIIIRA labelled microvessels in the white matter. Scale bar = 100 μm.