Table 1.

Expression pattern of genes encoding well-defined MC markers

Gene	MC ex vivo*			MC cultured†			Cultured + stimulated‡			(Next) Primary sample§	Mean all||
	D2	D3	D4	D1	D8	D5	D1	D8	D5
KIT	3 272	3 633	3268	4 426	2906	3 125	2094	1 261	2195	548 (melanocyte)	16
IL1RL1	656	1 156	418	487	340	423	1631	488	1073	423 (lung)	8
FCER1A	811	657	1087	2 699	1774	2 405	1211	1 670	2983	3272 (immature LC)	19
MS4A2	1 163	1 717	1284	2 173	1109	2 827	1580	533	1759	60 (basophil)	1
ENPP3	312	454	273	890	700	920	3209	1 116	1084	157 (basophil)	3
HDC	994	1 091	864	1 516	772	925	496	400	707	255 (basophil)	5
TPSAB1-TPSB2	2 536	1 332	2650	671	250	991	0	57	492	76 (stimulated MΦ)	0.1
TPSD1	552	783	558	317	972	1 585	40	518	925	5 (gallbladder)	0.2
CMA1	1 841	1 919	1240	631	119	1 210	502	203	624	8 (left atrium)	0.2
CPA3	5 057	6 001	2824	7 089	7295	7 883	7305	5 884	4386	239 (CD34+ diff. ery.)	4
CTSG	10 520	12 133	6902	14 981	7274	16 961	7000	10 752	9271	1278 (CD34+ BM)	37
HPGDS	1 245	1 220	1220	4 097	3088	3 545	3489	2 587	3182	333 (immature LC)	5
LTC4S	199	270	226	1 830	3261	1 684	81	1 478	329	194 (immature LC)	7

BM, bone marrow; CD34⁺ diff. ery. = CD34⁺ cells differentiated along the erythroid pathway; D, donor; LC, Langerhans cell; MΦ, macrophage.

^*Donor 2/donor 3/donor 4 (directly upon isolation from skin).

^†Donor 1/donor 8/donor 5 (MCs expanded in culture for 4-5 weeks).

^‡Donor 1 stimulated for 2.5 hours/donor 8 stimulated for 5 hours/donor 5 stimulated for 16 hours.

^§Nontransformed cell/tissue sample with the (second) highest expression of the gene.

^||Mean expression of all FANTOM5 non-MC samples. The values are given in (rounded) tags per million tags.