Figure 1.

Clinically useful algorithm for optimal consolidation for acute myeloid leukemia patients based on cytogenetic and molecular genetic aberrations, based on available data and practice preference. ¹Allogeneic HCT may be considered in medically fit AML patients with intermediate risk/normal cytogenetics in CR1. Bu/Cy: Busulfan/cyclophosphamide; CEBPA: CCAAT enhancer binding protein alpha; CR: Complete remission; dUCB: Double umbilical cord blood; FLT3-ITD: FMS-like tyrosine kinase 3 gene-internal tandem duplication; HCT-CI: Hematopoietic cell transplantation-comorbidity index; HDT: High dose therapy; HiDAC: High dose cytarabine; NPM: Nucleophosmin.