Variations in structure and composition across
the bilayer surface
(in the xy-plane). (a) The 3D shape of each monolayer
and the location of the aggregate. The upper and lower leaflet, described
by the average z-position of the PO4 beads, are in
gray and magenta, respectively, whereas the normalized probability
distribution of the protein is shown in a heat map from high (red)
to low (blue) density. (b) Change in thickness measured by the average
distance between the phosphate bead positions within each bin, colored
in red/orange for the Lo domain, blue/cyan for the Ld domain and green/yellow for the boundary between the two
domains. (c,d) Lipid number density distribution at the upper (c)
and lower (d) leaflets in blue (lowest density) through red (highest
density).