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. 2014 Mar 7;10:622–627. doi: 10.3762/bjoc.10.53

Table 1.

Survey of the photocatalytic bromination reaction conditions.

graphic file with name Beilstein_J_Org_Chem-10-622-i001.jpg
entry conditionsa yield (%)b
1 CH3CN, tube closed 78
2 CH3CN, N2 89
3 CH3CN, O2 46
4 CH3CN, open to air 94
5 CH3OH, open to air 23
6 CH2Cl2, open to air 0
7 DMF, open to air 63
8 THF, open to air 0
9 EtOAc, open to air 0
10 1,4-dioxane, open to air 0
11 CH3CN + 10 equiv H2O, open to air 0
12 DMSO, open to air 82
13 CH3CN, Ru(bpy)3Cl2 (3%), open to air 86

aReaction conditions: substrate 1a (0.1 mmol), CBr4 (0.1 mmol), Ru(bpy)3Cl2 (5 mol %), solvent (0.1 M), blue LEDs (1W). bYields were determined by GC analysis.