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. 2014 Apr 12;15:104. doi: 10.1186/1471-2105-15-104

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Copyright © 2014 Cantarel et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Effect of variant calling programs used as input on sensitivity and specificity of BAYSIC. SNP variants were detected with BAYSIC using as input all possible combinations FreeBayes, SamTools, GATK and Atlas. The sensitivity and specificity of each set was then measured as in Figure 4 for SNPs occurring in coding regions (top) or non-coding regions (bottom). The sensitivity and specificity for each combination of input call sets and for a range of posterior probability cutoffs is shown.