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. Author manuscript; available in PMC: 2014 Apr 25.
Published in final edited form as: J Bone Marrow Res. 2013 May 23;1:122. doi: 10.4172/2329-8820.1000122

Figure 3. Inhibition of invasive hMSCs toward SCM using the STAT3 inhibitor Stattic.

Figure 3

A) Matrigel invasion assays were seeded with 60,000 cells per well in RPMI and invaded toward SCM with or without 100 ng/mL of IL-6, and with or without 1 μM Stattic. After 24 hours the cells were stained using the Diffi-Quick Staining kit and 4 independent fields were counted and averaged. The experiment was repeated twice and each time no cells were able to invade toward SCM in the presence of Stattic.

B) Cell-titer glow experiment for cell proliferation of hMSCs treated with or without 1 μM Stattic for 24 hours