Table 3.
Immune Therapies Using Allogeneic Cells or Tissue
| Site/Investigator | Description | Disease | Study Phase - Enrollment |
References |
|---|---|---|---|---|
| City of Hope, Duarte, CA/B Badie | Allogeneic T Cells modified with chimeric IL-13α2 - TCRζ | brain tumor | I - 10 | 97 |
| Penn State Univ, Hershey, PA/ K Lucas | Allogeneic, CMV specific CTL | brain tumor | I/II - 10 | 98 |
| UCLA, Los Angeles, CA/L Liau & C Kruse | Alloreactive CTL and IL-2 | brain tumor | I - 15 | 93, 99 |
| NovaRx, San Diego, CA/H Fakhrai | Allogeneic Tumor Cell Vaccine with TGF 2 knockdown | non-small cell lung carcinoma and brain tumor | II -75 | 100 |
| Baylor, Houston, TX/J Fay | Autologous DC pulsed with Allogeneic Melanoma Tumor | melanoma | I/II - 33 | Clinicaltrials.gov, NCT00313235 |
| IDM Res Lab, Sanofi-Aventis, Paris, France/M Salcedo | Autologous DC pulsed with Allogeneic Melanoma Tumor | melanoma | I/II - 15 | 101 |
| Univ Pittsburgh, Pittsburgh, PA/ G Chatta | Autologous DC pulsed with Allogeneic Prostate Tumor | prostate cancer | I - 12 | Clinicaltrials.gov, NCT00970203 |