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. Author manuscript; available in PMC: 2014 Oct 1.
Published in final edited form as: J Immunol Methods. 2013 Jun 13;395(0):1–13. doi: 10.1016/j.jim.2013.06.001

Figure 8. Baseline Correction.

Figure 8

In RV144a, we plot three tracks of across-subject Z-scale normalized peptide intensity means as a function of their HxB2 position: means of peptides in pre-treatment samples, means of peptides in post-treatment samples, and the mean of the differences. A smoother line tracks overall trends. By visual inspection one sees that the pre and post-treatment tracks are highly similar. The differences are tightly centered around zero, except at positions experiencing a vaccine response. This indicates the presence of weak nonspecific effects that normalization cannot remove.