TABLE 2. Carbon Monoxide Diffusing Capacity in Post-Surfactant-Era Survivors of BPD.
| Study | Age | N(BPD) | GA(wk) | BW(g) | N(Con) | DLco | Kco | VA |
|---|---|---|---|---|---|---|---|---|
| Balinotti et al. | 11.6 mo | 39 | 26 | 870 | 61 | −20.6% | −10.2% | ND |
|
| ||||||||
| Korhonen et al. | 7 yr | 34 | 27 | 951 | 34 | −14.9% | −10.8% | NR |
|
| ||||||||
| Cazzato et al. | 8–9 yr | 22 | 26 | 840 | 46 | −1.17 (z-score) | −1.17 (z-score) | NR |
|
| ||||||||
| Kaplan et al. | 10 yr | 28 | 26.2 | 821 | 23 | − 13.6% | − 7.2% | NR |
|
| ||||||||
| Welsh et al. | 11 yr | 38 | 25 | 740 | 38 | −0.94 (z-score) | −0.73 (z-score) | NR |
Results reported are for BPD vs. term control.
BPD, bronchopulmonary dysplasia; BW, birthweight; Con, controls (term); DLco, single-breath diffusing capacity for carbon monoxide; g, grams; GA, gestational age; Kco, rate constant for carbon monoxide uptake per unit barometric pressure; mo, month; N, number of subjects; ND, no significant difference; NR, not reported; VA, alveolar volume; yr, year. Values reported are mean values.