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. Author manuscript; available in PMC: 2014 Apr 25.
Published in final edited form as: Circ Res. 2013 Sep 17;113(10):1169–1179. doi: 10.1161/CIRCRESAHA.113.302302

Figure 5. Enhanced proliferation, metabolic activity, and survival after Pim-1 modification of human cardiac progenitor cells (hCPCs) with fast- and slow-growth kinetics (hCPC-F and hCPC-S, respectively).

Figure 5

A, Increased population doubling time calculated by CyQuant and viability assay cell counts after Pim-1 modification (n=3). B and C, Increased proliferation rate and metabolic activity in genetically modified hCPC-S and hCPC-F with Pim-1 (n=3). D, Percentage of Annexin-V+ cells are measured by fluorescence activated cell sorting analysis after apoptotic stimuli of 30 μmol/L H2O2 shows increased cell survival after Pim-1 modification (n=3). *P<0.05, **P<0.01, ***P<0.001. Significance values are calculated for enhanced green fluorescent protein (eGFP) vs Pim in both hCPC groups.