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. 2014 Mar 20;14:213. doi: 10.1186/1471-2407-14-213

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Copyright © 2014 Martínez et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Validation of DNA hypermethylation events in malignant transformation of PXA. Representation of DNA methylation levels exhiited by the five selected markers on the GoldenGate DNA methylation assay (a) and validated by pyrosequencing on an independent set of samples (b).