Table 1.
Characteristic/factor |
Bivariate associations |
Multivariable associations‡ |
||||||||
---|---|---|---|---|---|---|---|---|---|---|
Fetal death | Infant death | |||||||||
|
Total* |
N |
% |
N |
% |
Odds ratio† |
Total |
Odds ratio† |
95% C.I. § |
P value |
Maternal race/ethnicity |
|
|
|
|
|
|
|
|
|
|
Other/Unknown |
258 |
161 |
62.4 |
97 |
37.6 |
1.53 |
240 |
1.28 |
0.86 – 1.90 |
.23 |
White |
3688 |
2511 |
68.1 |
1177 |
31.9 |
1.19 |
3511 |
1.13 |
0.87 – 1.47 |
.35 |
Black |
3616 |
2293 |
63.4 |
1323 |
36.6 |
1.47 |
3488 |
1.30 |
1.00 – 1.07 |
.050 |
Latino |
482 |
346 |
71.8 |
136 |
28.2 |
1 |
406 |
1 |
|
|
Birth weight (grams) |
|
|
|
|
|
|
|
|
|
|
< 500 |
3130 |
1773 |
56.6 |
1357 |
43.4 |
4.54 |
2986 |
6.39 |
4.73 – 8.64 |
< .001 |
500-750 |
1454 |
755 |
51.9 |
699 |
48.1 |
5.49 |
1397 |
7.42 |
5.43 – 10.1 |
< .001 |
751-1000 |
491 |
356 |
72.5 |
135 |
27.5 |
2.25 |
464 |
2.47 |
1.72 – 3.54 |
< .001 |
1001-1500 |
546 |
430 |
78.8 |
116 |
21.2 |
1.60 |
519 |
1.39 |
0.97 – 2.01 |
.077 |
1501-1800 |
309 |
246 |
79.6 |
63 |
20.4 |
1.52 |
292 |
1.25 |
0.82 – 1.91 |
.30 |
1801-2000 |
202 |
148 |
73.3 |
54 |
26.7 |
2.16 |
192 |
1.93 |
1.23 – 3.03 |
.004 |
2001-2500 |
457 |
372 |
81.4 |
85 |
18.6 |
1.35 |
438 |
1.32 |
0.90 – 1.94 |
.16 |
2501-4000 |
942 |
792 |
84.1 |
150 |
15.9 |
1.12 |
904 |
1.18 |
0.84 – 1.66 |
.35 |
> 4000 |
513 |
439 |
85.6 |
74 |
14.4 |
1 |
413 |
|
|
|
Gestational age |
|
|
|
|
|
|
†† |
|
|
|
< 24 weeks |
3907 |
2083 |
53.3 |
1824 |
46.7 |
2.92 |
|
|
|
|
24 weeks |
437 |
230 |
52.6 |
207 |
47.4 |
3.00 |
|
|
|
|
25 weeks |
294 |
197 |
67.0 |
97 |
33.0 |
1.64 |
|
|
|
|
26 weeks |
230 |
181 |
78.7 |
49 |
21.3 |
0.90 |
|
|
|
|
27 weeks |
185 |
151 |
81.6 |
34 |
18.4 |
0.75 |
|
|
|
|
28 weeks |
205 |
165 |
80.5 |
40 |
19.5 |
0.81 |
|
|
|
|
29-30 weeks |
339 |
268 |
79.1 |
71 |
20.9 |
0.88 |
|
|
|
|
31-32 weeks |
420 |
343 |
81.7 |
77 |
18.3 |
0.75 |
|
|
|
|
33-34 weeks |
398 |
329 |
82.7 |
69 |
17.3 |
0.70 |
|
|
|
|
35-36 weeks |
441 |
364 |
82.5 |
77 |
17.5 |
0.71 |
|
|
|
|
37-41 weeks |
1051 |
881 |
83.8 |
170 |
16.2 |
0.64 |
|
|
|
|
> = 42 weeks |
26 |
20 |
76.9 |
6 |
23.1 |
1 |
|
|
|
|
Delivery method |
|
|
|
|
|
|
|
|
|
|
Vaginal |
7060 |
4777 |
67.7 |
2283 |
32.3 |
1 |
6691 |
1 |
|
|
C-section |
946 |
497 |
52.5 |
449 |
47.5 |
1.89 |
914 |
3.76 |
3.16 – 4.48 |
< .001 |
Maternal medical history positive for diseases or predisposing conditions |
|
|
|
|
||||||
No |
4341 |
2949 |
67.9 |
1392 |
32.1 |
1 |
4091 |
1.09 |
0.97 – 1.20 |
.92 |
Yes |
3703 |
2362 |
63.8 |
1341 |
36.2 |
1.20 |
3514 |
1 |
|
|
Presence of any congenital anomaly |
|
|
|
|
|
|
|
|||
No |
7259 |
4902 |
67.5 |
2357 |
32.5 |
1 |
6880 |
1 |
|
|
Yes |
785 |
409 |
52.1 |
376 |
47.9 |
1.91 |
725 |
3.03 |
2.51 - .365 |
<.001 |
Prenatal care visits |
|
|
|
|
|
|
†† |
|
|
|
0-2 visits |
1228 |
756 |
61.6 |
472 |
38.4 |
1 |
|
|
|
|
3-7 visits |
3251 |
1968 |
60.5 |
1283 |
39.5 |
1.04 |
|
|
|
|
8-12 visits |
2004 |
1450 |
72.4 |
554 |
27.6 |
0.61 |
|
|
|
|
> = 13 visits |
1005 |
725 |
72.1 |
280 |
27.9 |
0.62 |
|
|
|
|
Maternal age (years) |
|
|
|
|
|
|
|
|
|
|
< 18 |
569 |
390 |
68.5 |
179 |
31.5 |
1.56 |
546 |
1.94 |
1.25 – 3.01 |
.003 |
18-19 |
807 |
518 |
64.2 |
289 |
35.8 |
1.90 |
785 |
2.25 |
1.49 – 3.40 |
< .001 |
20-24 |
2225 |
1435 |
64.5 |
790 |
35.5 |
1.88 |
2126 |
2.07 |
1.41 – 3.06 |
< .001 |
25-29 |
1975 |
1317 |
66.7 |
658 |
33.3 |
1.70 |
1870 |
1.76 |
1.19 – 2.59 |
.005 |
30-34 |
1441 |
907 |
62.9 |
534 |
37.1 |
2.01 |
1357 |
2.05 |
1.38 – 3.03 |
< .001 |
35-39 |
787 |
551 |
70.0 |
236 |
30.0 |
1.46 |
741 |
1.54 |
1.02 – 2.32 |
.041 |
> = 40 |
194 |
150 |
77.3 |
44 |
22.7 |
1 |
180 |
1 |
|
|
Maternal education |
|
|
|
|
|
|
|
|
|
|
Beyond college |
320 |
208 |
65.0 |
112 |
35.0 |
1.14 |
318 |
1.21 |
0.89 – 1.63 |
.23 |
College graduate |
884 |
541 |
61.2 |
343 |
38.8 |
1.34 |
877 |
1.36 |
1.10 – 1.69 |
.005 |
1-3 years of college |
1544 |
934 |
60.5 |
610 |
39.5 |
1.38 |
1530 |
1.35 |
1.13 – 1.62 |
.001 |
High school graduate |
2941 |
1970 |
67.0 |
971 |
33.0 |
1.04 |
2920 |
1.02 |
0.87 – 1.19 |
.84 |
Less than high school |
1976 |
1341 |
67.9 |
635 |
32.1 |
1 |
1960 |
1 |
|
|
Plural birth |
|
|
|
|
|
|
|
|
|
|
No |
7056 |
4825 |
68.4 |
2231 |
31.6 |
1 |
6653 |
1 |
|
|
Yes |
988 |
486 |
49.2 |
502 |
50.8 |
2.23 |
952 |
1.59 |
1.37 – 1.86 |
< .001 |
Geographic variation, birth hospital |
|
|
|
|
|
|
|
|||
Births in smaller counties |
1522 |
1087 |
71.4 |
435 |
28.6 |
1 |
1450 |
1 |
|
|
Out of hospital births |
140 |
95 |
67.9 |
45 |
32.1 |
1.18 |
118 |
2.29 |
0.99 – 5.27 |
.052 |
Low birth hospitals in larger counties |
228 |
174 |
76.3 |
54 |
23.7 |
0.78 |
210 |
0.62 |
0.30 – 1.27 |
.19 |
01 |
63 |
54 |
85.7 |
9 |
14.3 |
0.42 |
63 |
1.40 |
0.36 - 5.35 |
.63 |
02 |
107 |
91 |
85.0 |
16 |
15.0 |
0.44 |
100 |
1.18 |
0.46 - 3.04 |
.73 |
03 |
76 |
61 |
80.3 |
15 |
19.7 |
0.61 |
76 |
0.56 |
0.14 - 2.29 |
.42 |
04 |
106 |
85 |
80.2 |
21 |
19.8 |
0.62 |
100 |
0.91 |
0.35 - 2.32 |
.84 |
05 |
214 |
167 |
78.0 |
47 |
22.0 |
0.70 |
209 |
0.39 |
0.18 - 0.84 |
.016 |
06 |
99 |
77 |
77.8 |
22 |
22.2 |
0.71 |
98 |
0.32 |
0.09 - 1.13 |
.08 |
07 |
106 |
82 |
77.4 |
24 |
22.6 |
0.73 |
106 |
0.96 |
0.40 - 2.33 |
.93 |
08 |
545 |
410 |
75.2 |
135 |
24.8 |
0.82 |
537 |
0.54 |
0.34 - 0.84 |
.007 |
09 |
86 |
64 |
74.4 |
22 |
25.6 |
0.86 |
81 |
0.17 |
0.02 - 1.13 |
.067 |
10 |
105 |
78 |
74.3 |
27 |
25.7 |
0.86 |
101 |
0.59 |
0.20 - 1.72 |
.33 |
11 |
76 |
56 |
73.7 |
20 |
26.3 |
0.89 |
76 |
0.23 |
0.05 - 1.20 |
.08 |
12 |
127 |
93 |
73.2 |
34 |
26.8 |
0.91 |
121 |
0.95 |
0.39 - 2.33 |
.90 |
13 |
205 |
150 |
73.2 |
55 |
26.8 |
0.92 |
189 |
1.43 |
0.77 - 2.67 |
.26 |
14 |
147 |
103 |
70.1 |
44 |
29.9 |
1.07 |
144 |
0.61 |
0.29 - 1.29 |
.20 |
15 |
293 |
202 |
68.9 |
91 |
31.1 |
1.13 |
257 |
0.91 |
0.51 - 1.62 |
.75 |
16 |
97 |
66 |
68.0 |
31 |
32.0 |
1.17 |
96 |
1.05 |
0.44 - 2.50 |
.91 |
17 |
65 |
44 |
67.7 |
21 |
32.3 |
1.19 |
61 |
0.75 |
0.18 - 3.10 |
.69 |
18 |
237 |
159 |
67.1 |
78 |
32.9 |
1.23 |
213 |
1.60 |
0.81 - 3.19 |
.18 |
19 |
87 |
58 |
66.7 |
29 |
33.3 |
1.25 |
80 |
1.46 |
0.54 - 3.97 |
.46 |
20 |
69 |
45 |
65.2 |
24 |
34.8 |
1.33 |
69 |
0.95 |
0.31 - 2.93 |
.93 |
21 |
110 |
70 |
63.6 |
40 |
36.4 |
1.43 |
110 |
1.14 |
0.49 - 2.64 |
.76 |
22 |
106 |
66 |
62.3 |
40 |
37.7 |
1.51 |
102 |
0.47 |
0.15 - 1.44 |
.18 |
23 |
117 |
72 |
61.5 |
45 |
38.5 |
1.56 |
115 |
0.56 |
0.23 - 1.39 |
.22 |
24 |
332 |
200 |
60.2 |
132 |
39.8 |
1.65 |
307 |
1.40 |
0.82 - 2.41 |
.22 |
25 |
356 |
214 |
60.1 |
142 |
39.9 |
1.66 |
352 |
1.69 |
1.06 - 2.70 |
.027 |
26 |
288 |
170 |
59.0 |
118 |
41.0 |
1.73 |
276 |
1.04 |
0.58 - 1.86 |
.90 |
27 |
73 |
43 |
58.9 |
30 |
41.1 |
1.74 |
73 |
2.49 |
0.96 - 6.43 |
.060 |
28 |
364 |
197 |
54.1 |
167 |
45.9 |
2.12 |
363 |
1.55 |
0.97 - 2.46 |
.066 |
29 |
515 |
274 |
53.2 |
241 |
46.8 |
2.20 |
419 |
2.30 |
1.50 - 3.54 |
< .001 |
30 |
555 |
289 |
52.1 |
266 |
47.9 |
2.30 |
534 |
2.12 |
1.45 - 3.11 |
< .001 |
31 | 428 | 215 | 50.2 | 213 | 49.8 | 2.48 | 399 | 2.33 | 1.50 - 3.60 | < .001 |
*The total population of events was 8044. Four variables had missing data. Total records with data for these were: gestational age = 7933, prenatal care visits = 7488, maternal age = 7998, and maternal education = 7665.
† Odds of classification as infant (early neonatal) death compared to fetal death (reference group OR = 1). For bivariate associations, each listed variable had p < .001.
‡ There were 7605 records with data for the 9 variables included in the multivariable model. A logistic regression model using a one-stage cluster design (birth hospital) was used for this analysis.
§ C.I. = confidence interval.
†† Variable was not included in the modeling process (see text).