Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Mar 19;11:50. doi: 10.1186/1742-2094-11-50

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2014 Yanguas-Casás et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

TUDCA reduces microglial activation in the hippocampus of LPS treated mice. The effect of TUDCA on glial activation was determined by the immunoreactive area for Iba-1 (for microglial cells) (a–f) and GFAP (for astrocytes) (g–l) related to total area in mice hippocampus icv injected with LPS. Section treatments are as follows: 1 day control (a, g), 1 day icv LPS (b, h), 1 day icv LPS + ip TUDCA (c, i), 3 day control (d, j), 3 day icv LPS (e, k), and 3 day icv LPS + ip TUDCA (f, l).*P <0.05, ***P <0.001. Scale bar represents 100 μm. The results represent the mean ± SD of at least 5 sections of 6 animals per group.