. Author manuscript; available in PMC: 2014 Apr 25.

Published in final edited form as: Cell Cycle. 2008 May 12;7(14):2215–2224. doi: 10.4161/cc.7.14.6274

Table 5.

Top canonical pathways regulated by cyclins D1, D2 and D3

Pathway	p-value
Cyclin D1
Butanoate metabolism	0.002
p53 signaling	0.002
Fatty acid metabolism	0.003
Valine,leucine, isoleucine degradation	0.004
Tryptophan metabolism	0.005
Arginine and proline metabolism	0.013
Bile acid biosynthesis	0.018
Interferon signaling	0.019
Ascorbate and alderate metabolism	0.023
Propanoate metabolism	0.025
Metabolism of xenobiotics by cytochrome P450	0.030
Glycerolipid metabolism	0.040
Cyclin D2
Cell cycle: G₂/M DNA damage checkpoint regulation	0.0003
p53 signaling	0.0004
Antigen presentation pathway	0.012
Pyrimidine metabolism	0.016
Nicotinate and nicotinamide metabolism	0.019
Sonic hedgehog signaling	0.035
cAMP-mediated signaling	0.043
Cyclin D3
Cell cycle: G₂/M DNA damage checkpoint regulation	0.014