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. 2014 Mar 13;3(2):65–75. doi: 10.1002/open.201300040

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© 2014 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA.

This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Scheme 1 — Synthesis of novel benzamides as AT₂R ligands. Reagents and conditions: a) IleOtBu, HATU, DIEA, DMF, RT, 16 h; b) HNR¹R², Mo(CO)₆, DBU, Pd(OAc)₂, THF, MW 100 °C, 15 min; c) TFA/DCM (1:1), RT, 2 h.