Table 2. Linear regression of QTc, QT time and heart rate (HR) on sTNF-R1 in men and women (estimates with 95% confidence interval).

QTc [ms]	Men* [95% CI]	Women*[95% CI]	Men**[95% CI]	Women**[95% CI]
sTNF-R1 [1000 pg/mL]	5.41 [2.52, 8.30]	8.46 [4.81, 12.11]	−0.22 [−3.44, 3]	5.75 [1.32, 10.18]
hsCRP [10 mg/L]	6.8 [2.68, 10.92]	2.94 [0.71, 5.18]	2.17 [−1.96, 6.3]	2.02 [−0.23, 4.27]
IL-6 [10 pg/mL]	−0.11 [−0.93, 0.7]	−0.54 [−0.96, −0.12]	−0.2 [−0.98, 0.59]	−0.51 [−0.93, −0.09]

Estimates refer to a 1,000 pg/mL increase in sTNF-R1, a 10 pg/mL increase in IL-6, and a 10 mg/L increase in hsCRP.

*unadjusted values; ** covariate adjusted values: models were adjusted age, anti-arrhythmic (ATC code: C01B) and anti-phlogistic medication (ATC code: A07), current smoking status, high density lipoprotein (HDL), cholesterol, glucose blood level, alcohol intake, body mass index, thyroid stimulating hormone (TSH), systolic blood pressure and potentially QT prolonging drugs (see www.qtdrugs.org).

OR refers to a 1,000 pg/mL increase in sTNF-R1, a 10 pg/mL increase in IL-6, and a 10 mg/L increase in hsCRP.