Table 5. Multivariable logistic regression analysis for the listed outcomes among women age 35–44 and age 45 and older compared to women under age 35.
| Age 35–44, Adjusted ORa (95% CI),p-value | Age≥45, Adjusted ORa (95% CI), p-value | |
| Death | 1.92 (1.65, 2.24) <0.0001 | 7.48 (4.40, 12.2) <0.0001 |
| Mechanical ventilation | 1.71 (1.62, 1.80) <0.0001 | 1.12 (0.75, 1.69) 0.58 |
| Transfusion | 1.30 (1.28, 1.32) <0.0001 | 2.00 (1.82, 2.18) <0.0001 |
| Cardiac Events | ||
| Myocardial infarction/ischemia | 2.43 (1.94, 3.05) <0.0001 | 9.09 (4.69, 17.60) <0.0001 |
| Cardiac arrest/ventricular fibrillation | 1.88 (1.61, 2.21) <0.0001 | 7.94 (4.68, 13.48) <0.0001 |
| Acute heart failure | 1.76 (1.63, 1.90) <0.0001 | 5.09 (3.76, 6.89) <0.0001 |
| Pulmonary Events | ||
| Pneumonia | 1.68 (1.61, 1.76) <0.0001 | 1.82 (1.38, 2.40) <0.0001 |
| Pulmonary edema | 1.75 (1.58, 1.94) <0.0001 | 1.36 (0.74, 2.51) 0.33 |
| Thromboembolic Events | ||
| Pulmonary embolism | 1.70 (1.57, 1.85) <0.0001 | 3.39 (2.33, 4.92) <0.0001 |
| Deep vein thrombosis | 1.83 (1.73, 1.94) <0.0001 | 3.22 (2.39, 4.35) <0.0001 |
| Stroke/cerebrovascular disordersb | 1.7 (1.5, 1.9) <0.0001 | – (–, –) – |
| Infections | ||
| Sepsis | 1.32 (1.23, 1.40) <0.0001 | 1.76 (1.19, 2.61) 0.005 |
| Influenza | 1.15 (1.06, 1.25) 0.0008 | 1.10 (0.60, 2.00) 0.76 |
| Renal Event | ||
| Acute renal failure | 1.55 (1.46, 1.64) <0.0001 | 3.44 (2.67, 4.44) <0.0001 |
| Obstetric Events | ||
| Cesarean delivery | 1.57 (1.56, 1.57) <0.0001 | 2.10 (2.05, 2.16) <0.0001 |
| Operative vaginal delivery | 0.89 (0.88, 0.90) <0.0001 | 0.88 (0.83, 0.93) <0.0001 |
| Gestational diabetes | 2.34 (2.32, 2.35) <0.0001 | 3.02 (2.91, 3.13) <0.0001 |
| Prex, eclamp, gestational hypertension | 1.01 (1.004, 1.02) 0.0008 | 1.65 (1.59, 1.71) <0.0001 |
| Preterm labor | 1.07 (1.06, 1.07) <0.0001 | 1.12 (1.07, 1.16) <0.0001 |
| Abruption | 1.23 (1.21, 1.25) <0.0001 | 1.81 (1.65, 1.98) <0.0001 |
| Fetal growth restriction | 0.89 (0.88, 0.90) <0.0001 | 1.18 (1.10, 1.27) <0.0001 |
| Fetal demise | 1.24 (1.21, 1.27) <0.0001 | 2.08 (1.83, 2.37) <0.0001 |
| Cervical incompetence | 1.69 (1.66, 1.71) <0.0001 | 1.39 (1.25, 1.55) <0.0001 |
| Fetal chromosomal anomaly | 3.79 (3.64, 3.94) <0.0001 | 11.74 (10.07, 13.68) <0.0001 |
| Macrosomia | 1.22 (1.21, 1.23) <0.0001 | 1.09 (1.01, 1.18) 0.029 |
| Premature rupture of membranes | 1.10 (1.09, 1.11) <0.0001 | 1.24 (1.17, 1.32) <0.0001 |
| Placenta previa | 2.83 (2.79, 2.88) <0.0001 | 4.45 (4.09, 4.85) <0.0001 |
| Postpartum hemorrhage | 1.01 (1.005, 1.03) 0.0037 | 1.31 (1.22, 1.40) <0.0001 |
| Chorioamnionitis | 0.73 (0.72, 0.74) <0.0001 | 0.73 (0.66, 0.80) <0.0001 |
a
Adjusted OR for each condition while controlling for: insurance status, multiple gestation, chronic hypertension, chronic renal failure, cardiomyopathy, valvular heart disease, cardiac conduction disorders, history of myocardial infarction or chronic ischemia, asthma, diabetes, thyroid disorders, systemic lupus erythematosus/collagen vascular disease, rheumatoid arthritis, thrombophilia/APS, anemia, thrombocytopenia, drug use, alcohol use, and tobacco use.
b
There were less than 10 subjects with stroke/cerebrovascular disorders among women age 45 and older. The NIS does not allow the reporting of the number of subjects of any cell with 10 or less subjects.