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The role of the canonical Wnt, Ihh, Bmp and PTH/PTHrP signaling pathways in regulating the differentiation of mesenchymal precursors. The Wnt canonical pathway and Ihh, Bmp, PTH/PTHrP pathways control the commitment of mesenchymal precursors and also the differentiation of osteoblasts/osteocytes. Though these processes, they regulate the osteoblastogenesis and bone remodeling.
