Table 6.
Common chemotherapeutic agents involved in neuropathy process
Drug | Type | Onset, duration, recovery |
---|---|---|
Cisplatin | Chronic | 1–6 months for onset |
Carboplatin | Chronic | Years for recovery (more than 80%) |
Oxaliplatin | Acute or chronic Cold-induced | Acute: even during infusion Chronic: same as cisplatin Years for recovery (more than 80%) |
Taxanes | Chronic, rarely acute More with dose-dense taxane treatment | Onset within weeks 19% complete recovery 25% no recovery Paclitaxel-associated acute pain syndrome lasts 4–5 days |
Vincristine | Subacute | Onset usually after 3 months |
Vinblastine | Subacute | Recovery after 3 months of drug cessation |
Bortezomib | Onset any time, mainly subacute or chronic | Dose reduction is recommended |
Thalidomide | Dose-dependent | Recovery at 2 years or no recovery |
Ixabepilone | Subacute or chronic | Onset is acute or subacute |
Eribulin | Subacute or chronic | Quick recovery in mild cases Long-term data needed |