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. Author manuscript; available in PMC: 2014 Apr 25.
Published in final edited form as: Front Biosci (Landmark Ed). 2009 Jan 1;14:2203–2211. doi: 10.2741/3372

Figure 3.

Figure 3

Neuropeptides as mediators of vascular function and pain in tendon. Nerve fibres in normal and pathological tendons include sympathetic (NA: noradrenaline / adrenaline; NPY: neuropeptide Y), parasympathetic (Ach: acetylcholine), and sensory (SP: substance P; CGRP: calcitonin gene related peptide) nerve fibres, as well as free nerve endings expressing delta opioid receptors (δ OR). Tenocytes have been identified as both source and target of neuropeptide signals. Vascular regulation may occur via both direct and mast cell- or tenocyte-mediated mechanisms. Reproduced from Scott (BJSM, in press), with permission.