Table 3.
Enriched CD11b+ cell mRNA levels | ||||
---|---|---|---|---|
Gene | Sham Sal | Sham LPS | TBI Sal | TBI LPS |
iNOS | 1.15 ± 0.23 | 0.96 ± 0.30 | 1.47 ± 0.26 | 1.74 ± 0.51 |
Arg | 1.08 ± 0.14 | 1.75 ± 0.78 | 1.41 ± 0.22 | 1.01 ± 0.24 |
IL-4Rα | 1.61 ± 0.59 | 3.67 ± 1.64 | 4.29 ± 2.20 | 1.90 ± 0.60 |
Adult mice were subjected to a sham injury (sham) or moderate midline fluid percussion injury (TBI) (n=8–10). After 30 d, mice were injected i.p. with saline or LPS (0.33 mg/kg). Following the completion of the behavior tests (24 h), enriched brain CD11b+ cells were collected. The mRNA expression of inflammatory-associated genes (iNOS) and anti-inflammatory-associated genes (Arg, IL-4Rα) were determined. Values represent the mean ± SEM. Arg = arginase 1.