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. Author manuscript; available in PMC: 2014 Oct 3.
Published in final edited form as: Nat Commun. 2014 Apr 3;5:3509. doi: 10.1038/ncomms4509

Figure 5. Short periodic tracts of homology must be arrayed with the matching periodicity.

Figure 5

a, Ref/Test repeat pairs with 3-bp tracts of homology arrayed with matching periodicities of 10, 11, 12 and 13 bp.

b, Representative mutation profiles of repeat constructs in e.

c, The number of mutations for repeat constructs in e.

d, Repeat pairs with 3-bp tracts of homology arrayed with non-matching periodicities of 11 versus 9, 11 versus 12 and 11 versus 13 bp as compared to the original (matching) periodicity of 11 versus 11 bp.

e, Representative mutation profiles of repeat constructs in h.

f, The number of mutations for repeat constructs in h.

Data represent the mean number of mutations (per spore) over the total sequenced region. The number of analyzed crosses and spores is provided in Table 1. Error bars represent s.e.m. Mutation count distributions were compared by the two-sided Kolmogorov-Smirnov test: *** P < 0.001; NS P ≥ 0.05. Each mutation profile summarizes all RIP mutations found over the entire sequenced region in 30 spores obtained from a single cross.